• Butterfly glioblastoma: Clinical characteristics, treatment strategies and outcomes in a population-based cohort 

      Bjorland, Line; Kurz, Kathinka Dæhli; Fluge, Øystein; Gilje, Bjørnar; Mahesparan, Rupavathana; Sætran, Hege Aase; Ushakova, Anastasia; Farbu, Elisabeth (Peer reviewed; Journal article, 2022)
      Butterfly glioblastoma is a rare subgroup of glioblastoma with a bihemispheric tumor crossing the corpus callosum, and is associated with a dismal prognosis. Prognostic factors are previously sparsely described and optimal ...
    • Comprehensive ctDNA Measurements Improve Prediction of Clinical Outcomes and Enable Dynamic Tracking of Disease Progression in Advanced Pancreatic Cancer 

      Lapin, Morten; Edland, Karin Hestnes; Tjensvoll, Kjersti; Oltedal, Satu; Austdal, Marie; Garresori, Herish; Rozenholc, Yves; Gilje, Bjørnar; Nordgård, Oddmund (Peer reviewed; Journal article, 2023)
      Purpose: Circulating tumor DNA (ctDNA) has emerged as a promising tumor-specific biomarker in pancreatic cancer, but current evidence of the clinical potential of ctDNA is limited. In this study, we used comprehensive ...
    • Developing a Next-of-Kin Involvement Guide in Cancer Care—Results From a Consensus Process 

      Bergerød, Inger Johanne; Braut, Geir Sverre; Fagerdal, Birte; Gilje, Bjørnar; Wiig, Siri (Peer reviewed; Journal article, 2020)
      Background In hospital cancer care, there is no set standard for next-of-kin involvement in improving the quality of care and patient safety. There is therefore a growing need for tools and methods that can guide this ...
    • Effects of replacing PSA with Stockholm3 for diagnosis of clinically significant prostate cance in a health care system – the Stavanger Experience 

      Viste, Eirik; Vinje, Cathrine Alvær; Lid, Torgeir Gilje; Skeie, Svein; Evjen-Olsen, Øystein; Nordström, Tobias; Thorsen, Olav; Gilje, Bjørnar; Janssen, Emiel; Kjosavik, Svein Reidar (Peer reviewed; Journal article, 2020-08)
      Objective To describe early experience of replacing PSA with Stockholm3 for detection of prostate cancer in primary care. Design and methods Longitudinal observations, comparing outcome measures before and after the ...
    • Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer 

      Yndestad, Synnøve; Engebrethsen, Christina; Herencia-Ropero, A.; Nikolaienko, Oleksii; Vintermyr, Olav Karsten; Lillestøl, Reidun Kristine; Minsaas, Laura; Leirvaag, Beryl; Iversen, Gjertrud Titlestad; Gilje, Bjørnar; Blix, Egil Støre; Espelid, Helge; Lundgren, Steinar; Geisler, Jürgen; Aase, Hildegunn Siv; Aas, Turid; Gudlaugsson, Einar; Llop-Guevara, Alba; Serra, Violeta; Janssen, Emiel; Lønning, Per Eystein; Knappskog, Stian; Eikesdal, Hans Petter (Peer reviewed; Journal article, 2023)
      Purpose Homologous recombination deficiency (HRD) is highly prevalent in triple-negative breast cancer (TNBC) and associated with response to PARP inhibition (PARPi). Here, we studied the prevalence of HRD in non-TNBC to ...
    • Impact of extent of resection on outcome from glioblastoma using the RANO resect group classification system: a retrospective, population-based cohort study 

      Bjorland, Line; Mahesparan, Rupavathana; Fluge, Øystein; Gilje, Bjørnar; Kurz, Kathinka Dæhli; Farbu, Elisabeth (Peer reviewed; Journal article, 2023)
      Background Extent of resection (EOR) is associated with survival in glioblastoma. A standardized classification for EOR was lacking until a system was recently proposed by the response assessment in neuro-oncology (RANO) ...
    • Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway 

      Helland, Åslaug; Russnes, Hege Elisabeth Giercksky; Fagereng, Gro Live; Al-Shibli, Khalid Ibrahim; Andersson, Yvonne; Berg, Thomas; Bjørge, Line; Blix, Egil Støre; Bjerkehagen, Bodil; Brabrand, Sigmund; CAMERON, MARTE; Dalhaug, Astrid; Dietzel, Dalia; Dønnem, Tom; Enerly, Espen; Flobak, Åsmund; Fluge, Sverre; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Grønberg, Bjørn Henning; Grønås, Kari; Guren, Tormod Kyrre; Hamre, Hanne Mari; Haug, Åse; Heinrich, Daniel; Hjortland, Geir Olav; Hovig, Eivind; Hovland, Randi; Iversen, Ann-Charlotte; Janssen, Emiel; Kyte, Jon A; Gythfeldt, Hedda; Lothe, Ragnhild Adelheid; Lund, Jo-Åsmund; Meza, Leonardo Zepeda; Munthe-Kaas, Monica Cheng; Nguyen, Olav Toai Duc; Niehusmann, Pitt; Nilsen, Hilde; Puco, Katarina; Ree, Anne Hansen; Riste, Tonje Bøyum; Semb, Karin; Steinskog, Eli Sihn Samdal; Stensvold, Andreas; Suhrke, Pål; Tennøe, Øyvind Krohn; Tjønnfjord, Geir Erland; Vassbotn, Liv Jorunn; Aas, Eline; Aasebø, Kristine Øverås; Tasken, Kjetil; Smeland, Sigbjørn (Peer reviewed; Journal article, 2022)
      Background Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed ...
    • Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System 

      Nordgård, Oddmund; Forthun, Rakel Brendsdal; Lapin, Morten; Grønberg, Bjørn Henning; Kalland, Karl Henning; Kopperud, Reidun Kristin; Thomsen, Liv Cecilie Vestrheim; Tjensvoll, Kjersti; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Hovland, Randi (Peer reviewed; Journal article, 2021-04)
      Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers. We here present an overview of current evidence supporting the ...
    • Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen 

      Helland, Thomas; Naume, Bjørn; Hustad, Steinar; Bifulco, Ersilia; Kvaløy, Jan Terje; Sætersdal, Anna Barbro; Synnestvedt, Marit; Lende, Tone Hoel; Gilje, Bjørnar; Mjaaland, Ingvil; Weyde, Kjetil; Blix, Egil Støre; Wiedswang, Gro; Borgen, Elin; Hertz, Daniel Louis; Janssen, Emiel; Mellgren, Gunnar; Søiland, Håvard (Peer reviewed; Journal article, 2020)
      Low steady‐state levels of active tamoxifen metabolites have been associated with inferior treatment outcomes. In this retrospective analysis of 406 estrogen receptor‐positive breast cancer (BC) patients receiving adjuvant ...
    • Measuring next of kin satisfaction with hospital cancer care: using a mixed‐method approach as basis for improving quality and safety 

      Bergerød, Inger Johanne; Dalen, Ingvild; Braut, Geir Sverre; Gilje, Bjørnar; Wiig, Siri (Peer reviewed; Journal article, 2020)
      Aim/s To explore next of kin satisfaction with cancer care, map next of kin suggestions for involvement and combine this information to create a basis for improving quality and safety in hospitals. Design Convergent ...
    • Next-of-kin involvement in improving hospital cancer care quality and safety – a qualitative cross-case study as basis for theory development 

      Bergerød, Inger Johanne; Gilje, Bjørnar; Braut, Geir Sverre; Wiig, Siri (Journal article; Peer reviewed, 2018-05)
      Background Next-of-kin are an extension of healthcare professionals in all stages of cancer care. They offer care activities such as interpretations of symptoms, and reporting of negative or adverse effects of treatment, ...
    • Prenatal BRCA1 epimutations contribute significantly to triple-negative breast cancer development 

      Nikolaienko, Oleksii; Eikesdal, Hans Petter; Berge, Elisabet Ognedal; Gilje, Bjørnar; Lundgren, Steinar; Blix, Egil Støre; Espelid, Helge; Geisler, Jürgen; Geisler, Stephanie; Janssen, Emiel; Yndestad, Synnøve; Minsaas, Laura; Leirvaag, Beryl; Lillestøl, Reidun Kristine; Knappskog, Stian; Lønning, Per Eystein (Peer reviewed; Journal article, 2023)
      Background Normal cell BRCA1 epimutations have been associated with increased risk of triple-negative breast cancer (TNBC). However, the fraction of TNBCs that may have BRCA1 epimutations as their underlying cause is ...
    • Prostate Biopsies Can Be Omitted in Most Patients with a Positive Stockholm3 Test and Negative Prostate Magnetic Resonance Imaging 

      Vinje, Cathrine Alvær; Vigmostad, Maria Nyre; Kjosavik, Svein Reidar; Grönberg, Henrik; Gilje, Bjørnar; Skeie, Svein (Peer reviewed; Journal article, 2023-10)
      Background Magnetic resonance imaging (MRI) combined with the Stockholm3 test can be used to inform biopsy decision-making in patients with a suspicion of prostate cancer. Objective To determine the consequence of ...
    • Quality and safety in hospital cancer care : A mixed methods study of next of kin involvement 

      Bergerød, Inger Johanne (PhD thesis UiS;, Doctoral thesis, 2021-04)
      Introduction: Next of kin involvement in cancer care services is complex, challenging and influenced by factors related to the organisation of the healthcare service, the resources of the next of kin, and the patient’s ...
    • The role of microRNAs as predictors of response to tamoxifen treatment in breast cancer patients 

      Egeland, Nina; Lunde, Siri; Jonsdottir, Kristin; Lende, Tone Hoel; Cronin-Fenton, Deirdre P.; Gilje, Bjørnar; Janssen, Emilius Adrianus Maria; Søiland, Håvard (Journal article; Peer reviewed, 2015-10)
      Endocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. However, resistance to endocrine therapy leads to breast cancer relapse. The recent extension of adjuvant tamoxifen ...